Why don't we use topical antihistamines?

Adams

Well-known member
Topical histamines produce an itch response alone. Diphenhydramine does not count here because its MoA for this is different.
 

Bell

Active member
Isn't the MoA of diphenhydramine the H1-antagonism?

Also Dimetinden & Bamipin are used as topical H1-Antihistamines, like in Soventol gel or Fenistil gel.
 

Adams

Well-known member
Yeah, but its also a local anesthetic via sodium channel blocking which is its topical use.
 

Adams

Well-known member
Also Dimetinden & Bamipin are used as topical H1-Antihistamines, like in Soventol gel or Fenistil gel.
Oh cool, thanks! I’m guessing I’ve just never heard of them because they aren’t used in the US or are generally not popular.
 

Bell

Active member
No problem, gotta learn the German brand names now. I am starting my physical year in August.

At least for the OTC drugs. so keep asking about those 😄
 
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